Journals
The best choice for purification of virus and vaccine——QuikSep Sulfate
This introduction: In the field of biotechnology, affinity chromatography is often used to purify viruses and proteins. Affinity chromatography is a kind of adsorption chromatography, in which the target substances are selectively adsorbed on the ligands of column packing, and then the buffer is changed to achieve separation and recovery. Affinity chromatography is much more accurate than gel filtration or ion exchange chromatography in recovering target components. QuikSep Sulfate is a specific affinity filler, suitable for the isolation and purification of certain viruses, virus-like particles and certain antigens and proteins.
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chromatography packing life verification required equipment
This introduction: According to the quality control regulations for raw materials and excipients used in biological products production, part 3 of the 2015 edition of Chinese pharmacopoeia, chromatography packing is classified as grade 3 raw materials with medium risk, and corresponding quality control should be carried out. The third part of the 2015 edition of Chinese pharmacopoeia, general introduction of recombinant monoclonal antibody products for human use, requires verification of the acceptability of repeated use of purification materials. In addition, ICH, FDA and other relevant agencies also clearly pointed out the need to verify the service life of the chromatography filler.
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biological downstream intelligent purification high-end assembly
This introduction: In order to help promote the development of biological scientific research, we have introduced the elites of the automatic driving industry and the artificial intelligence research and development team, perfectly combined digital technology and biotechnology, and independently developed and manufactured the highly automated QuikSep A1 automatic chromatography system at the beginning of this year. The implementation of artificial intelligence oriented biological research development.
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The difference between industrial marijuana and drug marijuana in stage 121 and the analysis method
This introduction: Cannabis, as is generally understood, is a drug and is included in the restricted use of narcotic drugs by the United Nations commission on narcotic drugs. Actually, hemp is divided into industrial hemp, drug hemp and intermediate hemp. Industrial hemp is called hanma in China, and industrial hemp is widely used at home and abroad.
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第120期甘露醇的分析方法
This introduction: 甘露醇是山梨糖醇的同分异构体。在食品领域,用于麦芽糖、口香糖、年糕等视频的防粘,也可用作糖尿病患者用食品、健美食品等低热值、低糖的甜味剂。在医药领域是良好的利尿剂,甘露醇注射液作为高渗降压药,是临床抢救特别是脑部疾患抢救常用的一种药。以下介绍符合各国药典规定的甘露醇分析方法。
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第119期 连续流层析在血液制品纯化的应用
This introduction: 血液制品是指从人体血浆中分离提取出的各种人血浆蛋白制品,主要包括人血白蛋白、免疫球蛋白、凝血因子和其他蛋白成分。血液制品分离需采用低温乙醇沉淀分离法,各种蛋白在不同的条件下分步从溶液中析出。各组分精制则需采用层析方法,主要包括亲和层析和离子交换层析。
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第118期TLC薄层层析技术总结
This introduction: 薄层层析(TLC)是常用的一种分离和分析方法。 分类: 吸附薄层层析(硅胶) 分配薄层层析(纤维素) 薄层离子交换层析(离子交换剂) 薄层凝胶层析(分子筛凝胶) 硅胶:表面带有硅醇基(-Si-OH),呈弱酸性(pH=4.5),活性硅胶适合分离酸性或者中性化合物,如酚类、有机酸、甾体化合物以及氨基酸类,是基于吸附作用。非活性硅胶含有一定的水,在分离色素时是基于分配作用。 氧化铝:弱碱性(pH=9)、酸性(pH=4)及中性(pH=7.5)三种氧化铝。弱碱性氧化铝用来分离中性或碱性化合物;中性氧化铝适用于酸性及对碱不稳定的化合物的分离;酸性化合物可用酸性氧化铝分离。
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第117期连续流层析MCSGP在大麻二酚(CBD)纯化的应用
This introduction: 如何从预处理的大麻植物提取物中获得高纯度CBD? 如何将THC含量降低至要求范围内?
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第116期层析系统的压力监测及报警设置
This introduction: 层析填料都具是有最大耐压值的,如果层析填料实际承受压力超出最大耐压值,就有可能被压碎,影响填料的均匀程度,造成低柱效,甚至发生柱床塌陷,影响分离效果。
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第115期层析分离,是否一定要评价柱效?
This introduction: 流穿模式,是否需要评价柱效?亲和层析,单梯度洗脱,不用担心拖尾,是否需要评价柱效?
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